Release Notes 4.5 (May 2026)
Single-Machine Pipeline Execution
Pipelines can now be executed on a single machine in both Reproducible Runs (RR) and Cloud Workstations (CW), improving the developer experience by enabling faster iteration and more efficient pipeline testing
Run without AWS batch infrastructure — Ideal for development, testing, and quick iteration.
Faster startup times — Eliminate delays from infrastructure spin-up required for batch execution.
Compute resources can be configured in Pipeline Settings.
Nextflow v25 Support
Pipelines now support Nextflow v25.10.4 (latest), which introduces improvements to language validation and syntax handling, enhanced AWS Batch reliability, and multiple bug fixes for more stable pipeline execution. This ensures compatibility with modern workflows (e.g., nf-core pipelines) and keeps users aligned with the latest Nextflow capabilities.
Nextflow v25.10.4 will also be the default Nextflow version for all new Pipelines.
Hugging Face Credential Support
Users can now add Hugging Face user credentials and use them when importing models.
Hugging Face credentials support — Add your credentials to access gated resources.
Automatic credential detection — The system checks for credentials when importing from Hugging Face and uses them if available.
This enables seamless access to gated Hugging Face models that require authentication and agreement to provider terms.
Improved Collections Search Defaults
Search behavior has been updated to provide more intuitive default scopes across Collections:
My Organization defaults to Internal Collections
Public Collections defaults to Public Collections
Nested Collections default to Current Collection
This helps users find assets more easily by reducing empty search results caused by narrow default scopes.
Infrastructure Updates
Resource Watchdog
The services machine now reports CloudWatch metrics for all containers and CouchDB, to act as a memory safeguard that enhances overall system stability.
The existing top.py script, which monitored CPU and memory usage of OS processes on the services machine every minute and reported the top 7 processes to CloudWatch, has been replaced with a new comprehensive system monitor and memory safeguard called watchdog.py that runs on all Code Ocean EC2 instances and provides full visibility of the system by monitoring the following:
The top 25 processes
All running containers
Various OS parameters
RDS Postgres Upgrade
The RDS Postgres engine version was upgraded from version 17 to 18.
OpenSearch Automatic Software Update
The OpenSearch configuration was changed to allow automatic software updates, ensuring it stays up to date with the latest features and security patches.
Internal Docker Registry Upgrade
The internal Docker registry was upgraded from version 2.7.0 to version 3.1.0, bringing enhanced performance, and improved security and maintainability.
Aqua Model Upgrade
The model used by the Aqua AI Agent has been upgraded from Claude Sonnet 4.5 to Claude Sonnet 4.6, bringing improvements in performance, accuracy, and overall model capabilities.
Source AMI
al2023-ami-2023.11.20260413.0-kernel-6.1-x86_64
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